How i look forward to the day when no one needs to ask. The engine of adaptive evolution, natural selection, consists of two of the three parts of the evolutionary mechanism. Ib 169, evolutionary medicine syllabus, spring 2015 instructor. Evolutionary medicine, sometimes called darwinian medicine, is the field at the intersection of evolution and medicine. Evolution really tells us about sex, diet, and how we live by marlene zuk, 20. For biomedical scientists, medical students, and students of evolution, it is a valuable introduction to an important emerging field. When you see how evolution illuminates those questions, you see theres the potential for a new way of looking at them to save literally hundreds of millions of lives. Save up to 80% by choosing the etextbook option for isbn. Evolutionary perspectives on health and medicine stephen c. Stearns and ruslan medzhitov, evolutionary medicine. Modern medical research and practice have focused on the molecular and physiological mechanisms underlying health and disease, while evolutionary medicine focuses on the question of why evolution has shaped these mechanisms in ways that may leave us susceptible to. Evolutionary medicine bi 410510 crn 1454714555 fall 20. Evolutionary medicine refers to all the diverse places where the two endeavors intersect productively.
Evolutionary thinking in the medical sciences stephen c stearns, yale university, new haven, connecticut, usa evolutionary thinking in medicine draws both on the phylogenetic history of homo sapiens and on the dynamics of natural selection and genetic drift to give insight into antibiotic. Stearns and ruslan medzhitov, evolutionary medicine find, read and cite all the research you need on researchgate. Ib 169, evolutionary medicine syllabus, spring 2015. Evolution and medicine, professor stephen stearns, teaching fellow stephen john gaughran. Evolutionary medicine is a textbook intended for use in undergraduate, graduate, medical school, and continuing medical education cme courses. Evolutionary biology evolutionary genetics evolutionary medicine. Evolution and medicine, professor stephen stearns, teaching fellow vanessa lamers. The concept of biological evolution is among the most important ideas ever developed by applying scientific inquiry to the natural world nas and iom, 2008, and it offers many benefits to the field of medicine nesse and stearns, 2008. Evolution and medicine provides an accessible introduction to the new field of evolutionary medicine. Evolutionary medicine by stearns, stephen c medzhitov, ruslan and a great selection of related books, art and collectibles available now at. It does not include the heritable variation that enables a response to selection. Principles of evolutionary medicine is divided into three sections. Its professional illustrations and summaries of chapters and sections make its messages readily accessible.
He specializes in life history evolution, which links the fields of ecology and evolutionary biology, in evolutionary medicine, and in evolutionary functional genomics. He is known for his work in life history theory and evolutionary medicine. Perlman perspectives in biology and medicine, volume 56, number 2, spring 20, pp. Evolutionary biologists and physicians have traditionally been concerned with different problems and have developed different ways of approaching and understanding biological phenomena. Furthermore, it reveals that the body has no master plan and there is no such thing as the human genome. Evolutionary medicine first edition, 2016 by stearns and medzhitov students can opt to purchase a hard copy book available at the queens bookstore, and through other vendors or an ecopy. Evolutionary public health 1 evolutionary public health. Evolutionary medicine is not a field, like genetics or biochemistry. Ellison d a department of ecology and evolutionary biology, yale university, new haven, ct 06520. Antimicrobial amyloid the antagonistic pleiotropy between innate immunity and alzheimers disease, by emma healy 18. The hygiene hypothesis and the increase of cancer in the.
The aim of the lecture is to provide an indepth introduction to the main concepts in evolutionary biology and the most important evoolution mechanisms. Bass professor of ecology and evolutionary biology at yale university. This article has been cited by other articles in pmc. Evolutionary oral medicine eom, or darwinian dentistry, describes how em principles can be applied to exploring the evolutionary basis of modern dentofacial maladies. Pdf on feb 28, 2016, gilbert omenn and others published stephen c. Abstract evolutionary medicine is a new field whose goal is to incorporate an evolutionary perspective into medical education, research, and practice. On designing courses in evolutionary medicine stephen c. Instead, it consists of the intersections where evolutionary insights bring something new and useful to the medical profession, and where medical research offers new insights, questions. Evolutionary medicine is not a new specialty or method of practice or critique of medicine. Nesse3 1 center for evolution and cancer, university of california san francisco, ca, usa 2 department of psychology, arizona state university tempe, az, usa 3 department of psychiatry, the university of michigan ann arbor, mi, usa keywords. Evolutionary medicine bi 410510 crn 1579615795 fall 2011. Tom carlson 11815 1 ib 169, evolutionary medicine, spring 2015 instructor. Stearns is a professor of ecology and evolutionary biology at yale. First, the human female reproductive tract functions as a selection arena at two levels.
An evolutionary view offers a richer and more nuanced view of the body as a product of natural selection. Use the link below to share a fulltext version of this article with your friends and colleagues. What topics generate the most interest and the best. Evolutionary medicine and human evolution principles of macroevolution it is not unique ridley covers this ground well but the examples used are new and the hoektra features of the methods including potential pitfalls are quite clearlydescribed.
Stearns and medzhitov provide a valuable, authoritative resource for students encountering evolutionary medicine for the first time. Protection afforded by sickle cell trait against subtertian malarial infection. This cited by count includes citations to the following articles in scholar. Books his textbook is a great complement to the lectures as it also is written in a clear and understandable fashion.
On designing courses in evolutionary medicine stearns lab. Evolutionary medicine em is a growing field focusing on the evolutionary basis of human diseases and their changes through time. The exciting potential of evolutionary medicine to yield important new insights into longstanding questions about human physiology and pathophysiology was summed up by stearns. The hygiene hypothesis and the increase of cancer in the 20th century, by stacy scheuneman 14. Department of human evolutionary, biology, harvard university, cambridge, massachusetts search for more papers by this author first published.
Lf keller, p arcese, jnm smith, wm hochachka, sc stearns. Referring to the flipped classroom and active learning, stearns and medzhitov have made you tube and itunesu presentations for student online access under stearns evolutionary medicine, currently 65 videos, aimed at stimulating classroom discussion. Evolutionary medicine em, also known as darwinian medicine, 3 is a new approach providing a useful framework for understanding modern diseases from an evolutionary perspective. Warming the stone children is a true story of motherdaughter sexual abuse. Evolutionary applications to medicine and public health. Evolution, 2005, 596 pages, stephen stearns, rolf hoekstra. Evolutionary perspectives on health and medicine pnas. I am convinced your book will be widely used and make splendid service in many years to come. Evolution by natural selection has been biologys organizing principle for more than a century, but only in the last few decades has it been applied to the social sciences and medicine. Evolutionary thinking in the medical sciences evolutionary. Here, we propose a different approach by addressing more empirical and healthoriented research concerning past, current and. Stearns born december 12, 1946, in kapaau, hawaii and raised in hawi, hawaii is an american biologist, and the edward p. These selective filters early in life have implications both for eugenics and for the anti.
To date, the majority of em studies have used pure theories of hominin macroevolution to explain the presentday state of human health. Second, the evolutionary theory of aging predicts that intrinsic mortality should reflect extrinsic mortality. Evolutionary concepts help explain why we remain vulnerable to disease, how pathogens and cancer cells evolve, and how the diseases that affected our evolutionary ancestors have shaped our biology. It permeates biology, combining with physics and chemistry. It incorporates chapters on evolutionary processes, molecular evolution, the evolution of humans, life history theory, and evolutionarydevelopmental biology. In order to identify publication trends in evolutionary medicine, the author performed a bibliometric analysis of citations related to evolution and medicine using pubmed, the. Issues in evolutionary medicine issues in evolutionary medicine stearns, stephen c. Evolution and medicine is a better descriptor, but that has not caught on. It is a set of concepts and approaches with which to analyse many different parts of medical science. Courses in evolutionary medicine therefore cover a broad set of topics where evolutionary insights into medical issues have brought important advances that have the potential to. Issues in evolutionary medicine, american journal of human.1269 225 754 1601 858 366 757 1186 1568 433 1562 180 4 793 237 416 439 224 756 938 153 366 1237 1430 1332 56 617 1220 1052 1591 426 1150 288 32 47 1368 1267 1130 1443 422 1112 1052